Objective To research on influence of early hyperbaric oxygen complex treatment on cerebral vasospasm and neural function in patients after intracranial aneurysm clipping. Methods A total of 106 cases undergoing cerebral aneurysm clipping in the Department of Neurosurgery in our hospital between January 2013 and January 2017 were enrolled and randomly divided into observation group (53 cases) and control group (53 cases). The two groups were given regular therapy after operation, the observation group was continued with hyperbaric oxygen complex treatment. GOS, ADL and NFD scores were evaluated at discharge after treatment in the two groups. The middle cerebral artery velocity was measured and the number of cases of cerebral vasospasm was determined before complex treatment, after 15 and 30 days of complex treatment. Results There were significant differences in GOS, ADL and NFD scores between the two groups after therapy (P < 0.05), GOS and ADL scores in the observation group were higher than those in the control group, while NFD score was lower than that in the control group. There was no statistical difference in the middle cerebral artery velocity or the number of cases of cerebral vasospasm between the two groups before complex treatment (P > 0.05); however, the differences in the middle cerebral artery velocity and the number of cases of cerebral vasospasm were statistically significant between the two groups after 15 and 30 days of complex treatment (P < 0.05), the middle cerebral artery velocity in the observation was slower than that in the control group, the cases of cerebral vasospasm in the observation were fewer than those in the controls. Conclusions Early hyperbaric oxygen complex treatment has the positive meaning to recovery of nerve function after intracranial aneurysm clipping and can also reduce the occurrence of cerebral vasospasm.