Objective To evaluate the changes of left atrial function in patients with aortic stenosis (AS) by ultrasound speckle tracking imaging (STI), and to predict pulmonary circulation disorders and pulmonary edema at early stage. Methods IE33 color doppler ultrasound diagnostic instrument made by Philips was used to measure dynamic four-chamber, five-chamber and short-axis sectional view of cardiac apex in 30 AS patients and 30 healthy volunteers. Aortic valve orifice area (Aa), aortic valve orifice blood flow peak velocity (Av), left ventricular ejection fraction Simpson method, mitral valve orifice (E/A). Left atrial end-systolic volume (LAVS), left atrial end-diastolic volume (LAVD), left atrial p-volume (LAVp) and left atrial active ejection fraction (LAAEF) and left atrial passive ejection fraction (LAPEF) were recorded. Q-lab software was used to analyze and record peak left atrial deformation rate in left ventricular systole (SRs), peak left atrial deformation rate in early left ventricular diastole (SRe), and peak left atrial deformation rate in late left ventricular diastole (SRa). Results ①Compared to control group, Aa decreased, Av increased, E/A decreased, and LVEF decreased in AS group, and the differences were statistically significant (P < 0.05).②There was no significant difference in LAVD, LAVp, LAVS, LAPEF between two groups (P > 0.05); LAAEF decreased in AS group compared to control group (P < 0.05).③Compared with control group, SRs, SRe and SRa decreased in AS group, and the differences were statistically significant (P < 0.05). Conclusions STI changes in patients with aortic stenosis when all indexes are measured. Ultrasound speckle tracking imaging technology can detect early impaired left atrial function in patients with aortic stenosis, which is effective to predict the occurrence of pulmonary circulation and pulmonary edema, delay right heart failure and improve the prognosis.