Pregnancy-associated breast cancer is a special type of breast cancer, which occurs mostly in women of childbearing age and is rare in clinical practice. With the development of society, the incidence of the disease is increasing year by year. Due to the physiological proliferation of breast tissue during pregnancy, the delay of diagnosis is very common. Most of the clinical findings are in the middle and late stage. How to early screening, early diagnosis and early treatment, there are still many controversies about retaining patients’ fertility while improving their survival rate. This article reviews the clinical research progress of pregnancy-related breast cancer.