Objective To investigate the effects of atropine ophthalmic gel and compound tropamide eye drops on visual acuity and intraocular pressure in patients with malignant glaucoma. Methods Sixty eight patients (68 eyes) with malignant primary glaucoma admitted to our hospital from January 2016 to January 2018 were enrolled. According to different treatment methods, they were divided into observation group and control group. There were 34 cases (34 eyes) in both groups patient. The patients in both groups underwent phacoemulsification. The patients in the observation group were treated with atropine ophthalmic gel. The patients in the control group were treated with compound tropamide eye drops to compare the visual acuity and intraocular pressure of the two groups. Results The IOP after treatment in the observation group was lower than that in the control group, the anterior chamber depth was higher than that in the control group, and the difference was statistically significant (P?