Objective To investigate the relationship between thyrotropin receptor antibody (TRAb) and liver function in patients with Graves’ disease. Methods From January 2014 June 2018, 231 newly diagnosed patients with Graves’ disease were collected, including 178 female patients and 53 male patients. TRAb, thyroid function and liver function were measured in all patients. The correlation between abnormal liver function and TRAb in Graves’ disease was analyzed by nonparametric test, Logistic binary regression analysis and ROC curve. Results About 58.4% of the newly diagnosed patients with Graves’ disease had different degrees of liver function impairment. The levels of FT3 and FT4 increased significantly with the elevation of TRAb (P?