Objective To investigate the treatment and clinical outcomes in noncontiguous thoracolumbar fractures. Methods Fifty-three consecutive cases of noncontiguous thoracolumbar fractures in our hospital from December 2010 to January 2014 were retrospectively investigated, including 19 females and 34 males aged from 18 to 75 years (average 42 years). All patients were treated by conservative treatment or operation according to the type of fracture and bone mineral density (BMD). The clinical data of the patiants and radiographic information before and after operation and at last follow-up were summarized and analysed. ASIA was used to evaluate neurologic disability. Results All patients were followed up for 12-24 months. There was no infection and all incisions got primary healing without fixation failure. All the patients with spinal cord injury had neurological function recovery. Conclusions Application of individualized therapy according to the type of fracture and BMD of the patients can achieve satisfactory result in the treatment of noncontiguous thoracolumbar fractures.