Breast cancer has become one of the most frequently-occurred malignant tumors among Chinese women, while green therapy has turn into a new trend of tumor treatment. Therefore, exploration of new anti-cancer drugs has important significance for treatment of breast cancer. Curcumin, as an active ingredient of turmeric, was paid more attention by researchers and doctors, due to its inhibition of tumor cell proliferation, improving prognosis, reducing the reaction after chemotherapy. This article summarized the new research development of breast cancer cell’s proliferative inhibition mechanisms of drug delivery system of curcumin, function of synergy and attenuation of curcumin allying with chemotherapy and radiotherapy.