Objective To explore the change of tricuspid annular plane systolic excursion (TAPSE) and its correlation with glomerular filtration rate (GFR) in patients with acute decompensated heart failure (ADHF). Methods One hundred and two consecutive patients with acute decompensated heart failure and left ventricular ejection fraction (LVEF) below 50% on echocardiogram were enrolled. The value of TASPE, LVEF and pulmonary arterial systolic pressure (PASP) were measured by the transthoracic echocardiography. Blood test was conducted to determine NT-proBNP, electrolytes, BUN and creatinine. The estimated GFR (eGFR) was calculated on the basis of simplified Modification of Diet in Renal Disease (MDRD). According to the eGFR, the patients were divided into preserved renal function (PRF) group [eGFR ≥ 60 ml/（min·1.73m2）, n = 54] and renal dysfunction (RDSF) group [eGFR＜ 60 ml/
（min·1.73m2）, n = 48]. The echocardiographic parameters and serum indexes were compared between the two groups. The correlations between TASPE and echocardiographic parameters, serum indexes in the RDSF group were analyzed. Results  TASPE in the PRF group [(16.4 ± 4.0) mm] was significantly lower than that in the RDSF group [(18.9 ± 3.8) mm, P ＜ 0.001], but no significant difference in NT-proBNP, PASP or LVEF was observed between the two groups (P ＞ 0.05). In the PRF group TAPSE was positively correlated with eGFR (r = 0.62, P ＜ 0.05). Conclusions The decrease of TASPE is closely correlated with renal dysfunction in ADHF patients, and it may be a useful marker of predicting cardiorenal syndrome.