Objective To explore the therapeutic effect of repetitive facilitative exercise combined with EMG biofeedback on hand function in patients with hemiplegia and analyze its mechanism.Methods Ninety patients with hemiplegia were selected from the Department of rehabilitation medicine of the Second Affiliated Hospital of Qiqihar Medical College from May to December 2021, they were randomly divided into repetitive facilitative exercise group, EMG group, and combined group, with 30 people in each group. On this basis, repetitive facilitative exercise group was treated with repetitive facilitative exercise, EMG group was treated with EMG biofeedback, and the combined group was treated with repetitive facilitative exercise combined with EMG biofeedback. After 2 months of treatment, the Fugl‐Meyer motor function scale Ⅷ hand motor part score, hemiplegic hand function grade and maximum EMG limit value were compared among the three groups.Results Fugl-meyer finger function score difference between the three groups after 2 months of treatment and before treatment was statistically significant (P < 0.05), among which the combined group was higher than the Chuanping group and EMG group (P < 0.05). There was no significant difference between chuanping group and EMG group (P > 0.05). After 2 months of treatment, there was statistically significant difference in the hand function grade of hemiplegic patients in the three groups (P < 0.05), and the combined group was superior to chuanping group and EMG group (P < 0.05). There was no significant difference between chuanping group and EMG group (P > 0.05). After 2 months of treatment and before treatment, the EMG difference between the three groups was statistically significant (P < 0.05), and the combined group was higher than chuanping group and EMG group (P < 0.05). There was no significant difference between chuanping group and EMG group (P > 0.05).Conclusion Repetitive facilitative exercise combined with EMG biofeedback may promote the recovery of hand function in patients with hemiplegia by inducing muscle contraction and strengthening muscle strength.