Objective To explore the mediating effects of resilience between social support and stigma in cervical cancer patients.Methods The general information questionnaire, the Social Impact Scale (SIS), the Social Support Rating Scale (SSRS) and the Connor-Davidson Resilience Scale (CD-RISC) were used to survey 258 cervical cancer inpatients.Results The scores of SIS, SSRS and CD-RISC were (57.75 ± 8.890), (35.76 ± 7.499) and (54.65 ± 15.852) respectively. The stigma were negatively correlated with the social support (r = -0.347 ) and the resilience (r = -0.274) (P < 0.05 ), The resilience was positively correlated with the social support (r = 0.236, P < 0.05 ). The resilience had mediation effect between the social support and the stigma, and the mediation effect accounted for 12.22% of the total effect.Conclusions Social support plays an indirect effect on stigma in cervical cancer patients by the mediating effect of resilience, and the resilience can improve the inhibitory effect of social support on stigma in them.